British sailors who landed on Barbados in the 1620s at the site of present-day Holetown on the Caribbean coast found the island uninhabited. As elsewhere in the eastern Caribbean, Arawak Indians may have been annihilated by invading Caribs, who are believed to have subsequently abandoned the island.

From the arrival of the first British settlers in 1627-28 until independence in 1966, Barbados was a self-funding colony under uninterrupted British rule. Nevertheless, Barbados always enjoyed a large measure of local autonomy. Its House of Assembly, which began meeting in 1639, is the third-oldest legislative body in the Western Hemisphere, preceded only by Bermuda's legislature and the Virginia House of Burgesses.

As the sugar industry developed into the main commercial enterprise, Barbados was divided into large plantation estates, which replaced the small holdings of the early British settlers. Some of the displaced farmers relocated to British colonies in North America. To work the plantations, slaves were brought from Africa; the slave trade ceased a few years before the abolition of slavery throughout the British empire in 1834.

Plantation owners and merchants of British descent dominated local politics. It was not until the 1930s that the descendants of emancipated slaves began a movement for political rights. One of the leaders of this movement, Sir Grantley Adams, founded the Barbados Labour Party in 1938. Progress toward more democratic government for Barbados was made in 1951, when the first general election under universal adult suffrage occurred. This was followed by steps toward increased self-government, and in 1961, Barbados achieved the status of self-governing autonomy.

From 1958 to 1962, Barbados was one of 10 members of the West Indies Federation, and Sir Grantley Adams served as its first and only prime minister. When the federation was terminated, Barbados reverted to its former status as a self-governing colony. Following several attempts to form another federation composed of Barbados and the Leeward and Windward Islands, Barbados negotiated its own independence at a constitutional conference with the United Kingdom in June 1966. After years of peaceful and democratic progress, Barbados became an independent state within the British Commonwealth on November 30, 1966.